Fayrouz Cafe in Caroline Springs was lit on fire early on Thursday morning.
Emergency services were called to The Crossing, Caroline Springs about 2.10am after reports a car had been driven into a cafe and a fire occurred.
Fire crews extinguished the blaze and fortunately no one was injured. A crime scene guard is in place and an arson chemist will attend the scene later today.
Police will investigate whether the incident is linked to any other recent incidents.
Anyone with information is urged to contact Crime Stoppers on 1800 333 000 or at www.crimestoppersvic.com.au